In article number 1700759, Alexander Kros and co‐workers describe how mesoporous silica nanoparticles (MSNs) are delivered into cells via membrane fusion thereby omitting endocytosis pathways. Fusion is induced by a pair of complementary coiled‐coil lipopeptides inserted into the membrane of cells and in the bilayer of lipid‐coated MSNs. In this manner proteins can be efficiently delivered into the cytoplasm of cells.

中文翻译：

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介孔二氧化硅纳米粒子：膜融合介导脂质双层包被的介孔二氧化硅纳米粒子的细胞内递送（Adv。Healthcare Mater。20/2017）

Alexander Kros及其同事在文章编号1700759中描述了介孔二氧化硅纳米颗粒（MSN）如何通过膜融合作用传递到细胞中，从而省去了内吞途径。融合是由一对互补的卷曲螺旋脂肽插入细胞膜和脂质包裹的MSN双层中诱导的。以这种方式，蛋白质可以被有效地递送到细胞的细胞质中。