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Group 6 Dihapto-Coordinate Dearomatization Agents for Organic Synthesis
Chemical Reviews ( IF 62.1 ) Pub Date : 2017-10-24 00:00:00 , DOI: 10.1021/acs.chemrev.7b00480
Benjamin K. Liebov 1 , W. Dean Harman 1
Affiliation  

This review covers publications ranging from 2005 to 2017 concerning the organic reactions of aromatic ligands η2-coordinated to tungsten or molybdenum and the use of these reactions in the synthesis of novel organic substances. An emphasis is placed on C–C bond-forming reactions using conventional building blocks of organic synthesis such as acetals, enolates, Michael acceptors, acylating reagents, and activated aromatics. Substrates activated by the metal include arenes, pyridines, pyrroles, pyrimidines, furans, and thiophenes. General reactivity patterns are elucidated, as well as stereochemical preferences. These trends are compared to those of osmium and rhenium forebears as well as to the reactivity patterns of other methods of stoichiometric transition-metal-based dearomatization (i.e., η6-arene complexes).

中文翻译:

用于有机合成的第6组二配位脱芳香剂

这篇综述盖出版物范围2005至2017年关于芳族配体的有机反应η 2配位的,以钨或钼以及在新的有机物质的合成中使用的这些反应。重点放在使用有机合成的常规组成部分(如乙缩醛,烯醇盐,迈克尔受体,酰化试剂和活化的芳烃)的C-C键形成反应上。被金属活化的底物包括芳烃,吡啶,吡咯,嘧啶,呋喃和噻吩。阐明了一般的反应模式以及立体化学偏好。这些趋势相比,这些锇和铼祖先以及以化学计量为基础的过渡金属脱芳构化的其它方法(即,η的反应性模式6-芳烃配合物)。
更新日期:2017-10-24
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