G protein-coupled receptors (GPCRs) are ubiquitous gatekeepers of cellular response and signal predominantly by recruitment and activation of G proteins. In a recent paper in Nature, Flock et al. use large-scale bioinformatics to build a model of GPCR-G protein selectivity and an interactive database to interrogate potential receptor-G protein interactions.

中文翻译：

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编码GPCR-G蛋白特异性

G蛋白偶联受体（GPCR）是细胞反应的普遍守门人，主要通过募集和激活G蛋白来发出信号。在《自然》杂志的最新论文中，Flock等人。使用大规模的生物信息学来构建GPCR-G蛋白选择性模型和一个交互式数据库来询问潜在的受体G蛋白相互作用。