当前位置:
X-MOL 学术
›
Nat. Cell Biol.
›
论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Retriever fetches integrins from endosomes
Nature Cell Biology ( IF 21.3 ) Pub Date : , DOI: 10.1038/ncb3612 Catherine Rabouille
Nature Cell Biology ( IF 21.3 ) Pub Date : , DOI: 10.1038/ncb3612 Catherine Rabouille
Retriever fetches integrins from endosomes
更新日期:2017-10-12
Nature Cell Biology, Published online: 29 September 2017; doi:10.1038/ncb3612
Recycling from endosomes to the plasma membrane is an important step in cell homeostasis. The retromer/SNX27/WASH complex recycles numerous receptors, but key ones are still unaccounted for. Now a related conserved heterotrimer, called retriever, has been identified that, together with SNX17, the CCC complex and WASH, mediates the recycling of α5β1 integrins.