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Mononuclear Diploidy at the Heart of Cardiomyocyte Proliferation.
Cell Stem Cell ( IF 23.9 ) Pub Date : 2017-Oct-05 , DOI: 10.1016/j.stem.2017.09.012
Paula A. da Costa Martins

Reporting in Nature Genetics, Patterson et al. (2017) show that adult mammalian hearts possess an innate capacity to regenerate, which depends on a small population of mononuclear diploid cardiomyocytes. These cells undergo karyokinesis and cytokinesis, raising the possibility that endogenous cardiac muscle cells can be stimulated to proliferate for myocardial repair.

中文翻译:

单核二倍体在心肌细胞增殖的心脏。

帕特森(Patterson)等人在《自然遗传学》(Nature Genetics)中的报道。(2017)显示成年哺乳动物心脏具有先天再生的能力,这取决于一小部分单核二倍体心肌细胞。这些细胞经历核运动和胞质分裂,从而增加了刺激内源性心肌细胞增殖以进行心肌修复的可能性。
更新日期:2017-10-05
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