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Fluorescent Sensors Based on Aggregation-Induced Emission: Recent Advances and Perspectives
ACS Sensors ( IF 8.9 ) Pub Date : 2017-09-25 00:00:00 , DOI: 10.1021/acssensors.7b00551
Meng Gao 1 , Ben Zhong Tang 1, 2
Affiliation  

Fluorescent sensors with advantages of excellent sensitivity, rapid response, and easy operation are emerging as powerful tools in environmental monitoring, biological research, and disease diagnosis. However, conventional fluorophores featured with π-planar structures usually suffer from serious self-quenching in the aggregated state, poor photostability, and small Stokes’ shift. In contrast to conventional aggregation-caused quenching (ACQ) fluorophores, the newly emerged aggregation-induced emission fluorogens (AIEgens) are featured with high emission efficiency in the aggregated state, which provide unique opportunities for various sensing applications with advantages of high signal-to-noise ratio, strong photostability, and large Stokes’ shift. In this review, we will first briefly give an introduction of the AIE concept and the turn-on sensing principles. Then, we will discuss the recent examples of AIE sensors according to types of analytes. Finally, we will give a perspective on the future developments of AIE sensors. We hope this review will inspire more endeavors to devote to this emerging world.

中文翻译:

基于聚集诱导发射的荧光传感器:最新进展和展望

具有出色的灵敏度,快速响应和易于操作等优点的荧光传感器正在成为环境监测,生物学研究和疾病诊断中的强大工具。然而,具有π-平面结构特征的常规荧光团通常在聚集状态下遭受严重的自猝灭,光稳定性差和斯托克斯位移小。与传统的聚集引起的猝灭(ACQ)荧光团相反,新出现的聚集诱导的发射荧光素(AIEgens)在聚集状态下具有高发射效率,这为具有高信噪比优势的各种传感应用提供了独特的机会-噪声比大,光稳定性强,斯托克斯位移大。在这篇评论中,我们将首先简要介绍AIE概念和开启感应原理。然后,我们将根据分析物的类型讨论AIE传感器的最新示例。最后,我们将对AIE传感器的未来发展进行展望。我们希望这次审查会激发更多致力于这个新兴世界的努力。
更新日期:2017-09-25
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