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Colorimetric Sensor Array Based on Gold Nanoparticles with Diverse Surface Charges for Microorganisms Identification
Analytical Chemistry ( IF 7.4 ) Pub Date : 2017-09-25 00:00:00 , DOI: 10.1021/acs.analchem.7b02594
Bingyu Li 1 , Xizhe Li 1 , Yanhua Dong 1 , Bing Wang 1 , Dongyang Li 1 , Youmin Shi 1 , Yayan Wu 1
Affiliation  

We report a simple and novel colorimetric sensor array for rapid identification of microorganisms. In this study, four gold nanoparticles (AuNPs) with diverse surface charges were used as sensing elements. The interactions between AuNPs and microorganisms led to obvious color shifts, which could be observed by the naked eye. A total of 15 microorganisms had their own response patterns and were differentiated by linear discriminant analysis (LDA) successfully. Moreover, microorganism mixtures could also be well discerned. The method is simple, fast (within 5 s), effective, and visual, showing the potential applications in pathogen diagnosis and environmental monitoring.

中文翻译:

基于具有不同表面电荷的金纳米粒子的比色传感器阵列,用于微生物鉴定

我们报告了一种简单新颖的比色传感器阵列,可快速识别微生物。在这项研究中,四个具有不同表面电荷的金纳米颗粒(AuNPs)被用作传感元件。AuNP与微生物之间的相互作用导致明显的色移,这可以用肉眼观察到。共有15种微生物具有自己的反应模式,并通过线性判别分析(LDA)成功进行了区分。此外,还可以很好地识别微生物混合物。该方法简单,快速(5秒以内),有效且直观,显示了在病原体诊断和环境监测中的潜在应用。
更新日期:2017-09-25
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