The rebound mechanism for alkane hydroxylation was invoked over 40 years ago to help explain reactivity patterns in cytochrome P450, and subsequently has been used to provide insight into a range of biological and synthetic systems. Efforts to model the rebound reaction in a synthetic system have been unsuccessful, in part because of the challenge in preparing a suitable metal-hydroxide complex at the correct oxidation level. Herein we report the synthesis of such a complex. The reaction of this species with a series of substituted radicals allows for the direct interrogation of the rebound process, providing insight into this uniformly invoked, but previously unobserved process.

中文翻译：

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用氢氧化铁配合物直接观察氧回弹

烷烃羟基化的回弹机制在 40 多年前被用来帮助解释细胞色素 P450 的反应模式，随后被用于深入了解一系列生物和合成系统。在合成系统中模拟回弹反应的努力没有成功，部分原因是在正确的氧化水平下制备合适的金属氢氧化物络合物的挑战。在此我们报告了这种复合物的合成。该物种与一系列取代基团的反应允许直接询问回弹过程，从而深入了解这个统一调用但以前未观察到的过程。