A new tobacco filler Standard Reference Material (SRM) has been issued by the National Institute of Standards and Technology (NIST) in September 2016 with certified and reference mass fraction values for nicotine, N-nitrosonornicotine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, and volatiles. The constituents have been determined by multiple analytical methods with measurements at NIST and at the Centers for Disease Control and Prevention, and with confirmatory measurements by commercial laboratories. This effort highlights the development of the first SRM for reduced nicotine and reduced tobacco-specific nitrosamines with certified values for composition.

中文翻译：

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卷烟烟草填充料标准参考材料的开发

美国国家标准技术研究院（NIST）于2016年9月发布了一种新的烟草填充剂标准参考物质（SRM），其中含有尼古丁，N-硝基异烟碱，4-（甲基亚硝基氨基）-1-（ 3-吡啶基）-1-丁酮和挥发物。成分已通过多种分析方法进行了测定，这些方法在NIST和疾病控制与预防中心进行了测定，并在商业实验室进行了确认性测定。这项工作突显了第一个SRM的开发，该产品具有减少烟碱和减少烟草特有的亚硝胺的成分认证值。