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Resolving CNS mRNA Heterogeneity: Examining mRNA Alternative Polyadenylation at a Cell-Type-Specific Level.
Neuron ( IF 16.2 ) Pub Date : 2017-Sep-13 , DOI: 10.1016/j.neuron.2017.08.045
Martine Therrien , Myriam Heiman

Alternative polyadenylation often regulates mRNA isoform usage. In this issue of Neuron, Hwang et al. (2017) describe a powerful new cell-type-specific methodology, cTag-PAPERCLIP, which can be used to study alternative polyadenylation in the CNS.

中文翻译:

解决CNS mRNA异质性:在特定细胞类型的水平上检查mRNA替代性聚腺苷酸化。

替代的聚腺苷酸化经常调节mRNA同工型的使用。在本期《神经元》中,Hwang等人。(2017)描述了一种功能强大的新细胞类型特异性方法cTag-PAPERCLIP,可用于研究CNS中的替代聚腺苷酸化作用。
更新日期:2017-09-20
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