The transcriptional repressor Id2 is constitutively expressed in all innate lymphoid cells (ILCs) and is required for their development. In this issue of Immunity, Mowel et al. (2017) demonstrate that Id2 expression is regulated by a cell type-specific cis-regulatory element in group 1 ILCs that is demarcated by a long non-coding RNA.

中文翻译：

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将Id2转换为ILC1

转录抑制因子Id2在所有先天淋巴样细胞（ILC）中组成性表达，并且是其发育所必需的。在本期《免疫》中，Mowel等人。（2017）证明Id2表达受第1组ILC中特定于细胞类型的顺式调控元件的调控，该元件由长的非编码RNA划定。