Selective C–H activation is an area of growing importance in modern organic chemistry. Herein, we report our efforts in combining organocatalysis and photocatalysis for the development of a highly efficient and selective visible-light mediated protocol for the C–H activation and addition of various alcohols to a plethora of Michael acceptors, followed by a cyclization reaction leading to lactones, a repeatedly occurring motif in nature. Utilizing phenylglyoxylic acid as the photocatalyst and common household bulbs as the light source, we describe a versatile α-alkylation/lactonization of alcohols with α,β-unsaturated esters leading to products in excellent yields. The reaction mechanism was extensively studied.

中文翻译：

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通过醇的选择性C–H活化–烷基化反应进行光有机催化内酯的合成

选择性C–H活化是现代有机化学中日益重要的一个领域。在此，我们报告了我们在有机催化和光催化相结合方面的努力，以开发高效且选择性的可见光介导的C–H活化方案，并向大量Michael受体添加各种醇，然后进行环化反应，内酯，自然界中反复出现的基序。我们使用苯乙醛酸作为光催化剂，并用普通的家用灯泡作为光源，我们描述了醇与α，β-不饱和酯的多用途α-烷基化/内酯化，可产生高收率的产品。反应机理得到了广泛的研究。