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Oximes as reusable templates for the synthesis of ureas and carbamates by an in situ generation of carbamoyl oximes
Green Chemistry ( IF 9.8 ) Pub Date : 2017-08-03 00:00:00 , DOI: 10.1039/c7gc01449j
Gopal Chandru Senadi,Mohana Reddy Mutra,Ting-Yi Lu,Jeh-Jeng Wang

Oximes have been identified as reusable templates for the synthesis of ureas and carbamates by an in situ generation of carbamoyl oximes under metal-free conditions. The recovered oxime has been utilised for three trials in the synthesis of urea derivatives without any loss in the yield and efficiency. In addition, this template approach could override the usage of hazardous and less stable isocyanates as substrates.

中文翻译:

肟作为可重复使用的模板,可通过原位生成氨基甲酰基肟来合成尿素和氨基甲酸酯

通过在无金属条件下原位生成氨基甲酰基肟,已将肟确定为可重复使用的模板,用于合成尿素和氨基甲酸酯。回收的肟已用于尿素衍生物合成的三个试验中,而收率和效率没有任何损失。此外,这种模板方法可以替代使用危险性和不稳定度较高的异氰酸酯作为底物。
更新日期:2017-09-19
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