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Radical Hydrodehalogenation of Aryl Bromides and Chlorides with Sodium Hydride and 1,4-Dioxane
Angewandte Chemie International Edition ( IF 16.6 ) Pub Date : 2017-09-19 08:06:15 , DOI: 10.1002/anie.201706534
Tobias Hokamp 1 , Abhishek Dewanji 1 , Maximilian Lübbesmeyer 1 , Christian Mück-Lichtenfeld 1 , Ernst-Ulrich Würthwein 1 , Armido Studer 1
Affiliation  

It is the combo! NaH in combination with 1,4-dioxane serves as the reagent for the radical chain reduction of various aryl halides. Hydrodehalogenation is initiated by 1,10-phenanthroline (phen) at elevated temperature and can be combined with a typical radical cyclization reaction. the reactions proceed via electron catalysis.

中文翻译:

氢化钠和1,4-二恶烷对芳族溴化物和氯化物的自由基加氢脱卤

这是组合!NaH与1,4-二恶烷的组合用作各种芳基卤化物自由基链还原的试剂。加氢脱卤化反应是在高温下由1,10-菲咯啉(phen)引发的,可与典型的自由基环化反应结合使用。反应通过电子催化进行。
更新日期:2017-09-19
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