The FASTK family proteins have recently emerged as key post-transcriptional regulators of mitochondrial gene expression. FASTK, the founding member and its homologs FASTKD1–5 are architecturally related RNA-binding proteins, each having a different function in the regulation of mitochondrial RNA biology, from mRNA processing and maturation to ribosome assembly and translation. In this review, we outline the structure, evolution and function of these FASTK proteins and discuss the individual role that each has in mitochondrial RNA biology. In addition, we highlight the aspects of FASTK research that still require more attention.

中文翻译：

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FASTK蛋白质家族：线粒体RNA生物学的新兴调节剂。

FASTK家族蛋白最近已成为线粒体基因表达的关键转录后调节剂。FASTK（其创始成员及其同系物FASTKD1-5）是与体系结构相关的RNA结合蛋白，从mRNA加工和成熟到核糖体组装和翻译，每种蛋白在线粒体RNA生物学调控中均具有不同的功能。在这篇综述中，我们概述了这些FASTK蛋白的结构，进化和功能，并讨论了它们各自在线粒体RNA生物学中的作用。此外，我们重点介绍了FASTK研究方面仍需要更多关注的方面。