Photothermal desorption of molecules from plasmonic nanoparticles is an example of a light-triggered molecular release due to heating of the system. However, this phenomenon ought to work only if the molecule–nanoparticle interaction is exothermic in nature. In this study, we compare protein adsorption behavior onto gold nanoparticles for both endothermic and exothermic complexation reactions, and demonstrate that Le Chatelier’s principle can be applied to predict protein adsorption or desorption on nanomaterial surfaces. Polyelectrolyte-wrapped gold nanorods were used as adsorption platforms for two different proteins, which we were able to adsorb/desorb from the nanorod surface depending on the thermodynamics of their interactions. Furthermore, we show that the behaviors hold up under more complex biological environments such as fetal bovine serum.

中文翻译：

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Le Chatelier原理的纳米论证

来自等离子体纳米颗粒的分子的光热解吸是由于系统的加热而光触发的分子释放的一个例子。但是，只有分子与纳米粒子之间的相互作用本质上是放热的，这种现象才应该起作用。在这项研究中，我们比较了吸热和放热络合反应时蛋白质在金纳米颗粒上的吸附行为，并证明Le Chatelier原理可用于预测蛋白质在纳米材料表面的吸附或解吸。聚电解质包裹的金纳米棒被用作两种不同蛋白质的吸附平台，我们能够根据其相互作用的热力学从纳米棒表面进行吸附/解吸。此外，