A palladium‐catalyzed oxa‐[4+2] annulation of para‐quinone methides with allyl carbonates bearing a nucleophilic alcohol side chain has been developed. This method provided an efficient strategy to the construction of 2‐oxaspiro‐cyclohexadienones via 1,6‐conjugated addition‐mediated allylation in moderate to good yields. Preliminary results on asymmetric derivatives promised potential in the synthesis of enantioenriched frameworks.

中文翻译：

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钯催化的对醌甲基苯甲酸酯的Oxa- [4 + 2]环化

已经开发了钯催化的对苯二甲酰甲基与含烯丙基醇侧链的碳酸烯丙酯的氧杂[4 + 2]环化反应。该方法通过1​​,6-缀合的加成介导的烯丙基化以中等至良好的产率为2-氧杂螺环-环己二酮的构建提供了有效的策略。关于不对称衍生物的初步结果有望在对映体富集的框架的合成中具有潜力。