In Contrast to the Monsanto homogeneous system, the Rh heterogeneous methanol carbonylation universally displays lower activity and stability. Here, a single site catalyst Rh-POL-PPh₃ was successfully prepared by impregnation of the Rh₂(CO)₄Cl₂ dichloromethane solution, and applied to heterogeneous methanol carbonylation in a continuous fixed-bed reactor for the first time. Due to single site Rh species and the electron-donating effect of P ligands and the strong multicoordination bonds between Rh and P, the Rh-POL-PPh₃ catalyst exhibited a little higher TOF of 1550 h⁻¹ than that of optimized Monsanto process and maintained relatively stable activity for near 180 h under 2.5 MPa, 195 °C. Thus, POL-PPh₃ not only acts as a stable support but also a promotion of methanol carbonylation process.

与孟山都均相系统相反，Rh异质甲醇羰基化普遍显示出较低的活性和稳定性。在此，通过浸渍Rh ₂（CO）₄ Cl ₂二氯甲烷溶液成功制备了单中心催化剂Rh-POL-PPh ₃，并首次将其用于连续固定床反应器中的非均相甲醇羰基化。由于具有单一位点的Rh物种和P配体的电子给体作用以及Rh与P之间的强多配位键，Rh-POL-PPh ₃催化剂的TOF略高，为1550 h ^-1与优化的孟山都（Monsanto）工艺相比，在2.5 MPa，195°C的温度下保持了近180小时的相对稳定的活性。因此，POL-PPh ₃不仅充当稳定的载体，而且促进甲醇羰基化过程。