In this paper, a novel molecularly imprinted electrochemical sensor (MIECS) based on a glassy carbon electrode (GCE) modified with graphene quantum dots (GQDs) coated on hollow nickel nanospheres (hNiNS) for the rapid determination of bisphenol S (BPS) was proposed for the first time. HNiNS and GQDs as electrode modifications were used to enlarge the active area and electron-transport ability for amplifying the sensor signal, while molecularly imprinted polymer (MIP) film was electropolymerized by using pyrrole as monomer and BPS as template to detect BPS via cyclic voltammetry (CV). Scanning electron microscope (SEM), energy-dispersive spectrometry (EDS), CV and differential pulse voltammetry (DPV) were employed to characterize the fabricated sensor. Experimental conditions, such as molar ratio of monomer to template, electropolymerization cycles, pH, incubation time and elution time were optimized. The DPV response of the MIECS to BPS was obtained in the linear range from 0.1 to 50 μM with a low limit of detection (LOD) of 0.03 μM (S/N = 3) under the optimized conditions. The MIECS exhibited excellent response towards BPS with high sensitivity, selectivity, good reproducibility, and stability. In addition, the proposed MIECS was also successfully applied for the determination of BPS in the plastic samples with simple sample pretreatment.

本文提出了一种新型的分子印迹电化学传感器（MIECS），该传感器基于玻璃碳电极（GCE）修饰的石墨烯量子点（GQDs）修饰在空心镍纳米球（hNiNS）上，用于快速测定双酚S（BPS）。首次。使用HNiNS和GQDs作为电极修饰物来扩大活性区域和电子传输能力以放大传感器信号，同时以吡咯为单体并以BPS为模板对分子印迹聚合物（MIP）膜进行电聚合，以通过循环伏安法检测BPS（简历）。使用扫描电子显微镜（SEM），能量色散光谱（EDS），CV和差分脉冲伏安法（DPV）来表征所制造的传感器。实验条件，例如单体与模板的摩尔比，电聚合循环，优化了pH，孵育时间和洗脱时间。在优化条件下，MIECS对BPS的DPV响应在0.1至50μM的线性范围内获得，最低检测限（LOD）为0.03μM（S / N = 3）。MIECS对BPS表现出出色的响应性，具有高灵敏度，选择性，良好的重现性和稳定性。此外，所提出的MIECS还可以通过简单的样品前处理方法成功地用于测定塑料样品中的BPS。