Online transformations possible in carbon-11 chemistry: (i) Reduction with molybdenum at 850 °C; (ii) coupling of [¹¹C]CO₂ with vinylmagnesium bromide and quenching with water or Fischer esterification; (iii) coupling of [¹¹C]CO with vinyl iodide and Pd-xantphos with tert-butyl alcohol or tritylamine; (iv) Michael addition with base.

中文翻译：

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11C-丙烯酸酯，11C-丙烯酰胺的高效合成及其在PET示踪剂开发的迈克尔加成反应中的应用

碳11化学中可能的在线转化：（i）在850°C下用钼还原；（ii）将[ ¹¹ C] CO ₂与乙烯基溴化镁偶合，并用水淬灭或费歇尔酯化；（iii）[ ¹¹ C] CO与碘化乙烯和Pd-xantphos与叔丁醇或三苯甲基胺的偶合；（iv）迈克尔加基。