Two steps forward… Copper-exchanged metal–organic frameworks (MOFs) show tunable basicity, activity, and selectivity in C−C bond-forming reactions. Herein, these MOFs are used as selective heterogeneous catalysts for the one-pot, two-step (Henry reaction/Michael-type addition) synthesis of neuroactive pharmaceutical intermediates starting from nitromethane and benzaldehyde.

中文翻译：

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使用轻度碱度的金属有机骨架作为非均相催化剂的选择性一锅两步CC键形成

向前迈出了两步...铜交换的金属有机骨架（MOF）在C-C键形成反应中显示出可调节的碱度，活性和选择性。在本文中，这些MOF用作一锅，两步（亨利反应/迈克尔型加成）合成从硝基甲烷和苯甲醛开始的神经活性药物中间体的选择性多相催化剂。