RNA viruses circulate as rapidly evolving swarms of related variants, and their evolutionary dynamics within hosts may be key to understanding virus emergence. In this issue of Cell Host & Microbe, Parameswaran et al. (2017) combine next-generation sequencing and functional studies to characterize viral populations in acute dengue infections.

中文翻译：

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登革热宿主内部进化的驱动力

RNA病毒以迅速发展的相关变体形式传播，它们在宿主内的进化动力学可能是了解病毒出现的关键。在本期《细胞宿主与微生物》中，Parameswaran等人。（2017）将下一代测序和功能研究相结合，以表征急性登革热感染中的病毒种群。