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Revolving Vernier Mechanism Controls Size of Linear Homomultimer
Small ( IF 13.3 ) Pub Date : 2017-09-12 , DOI: 10.1002/smll.201702158
Takeo Uchida 1 , Keita Abe 1 , Yuma Endo 1 , Shosei Ichiseki 1 , Satoru Akita 1 , Shiyun Liu 1 , Sho Aradachi 1 , Masataka Saito 1 , Akihiko Fukuchi 1 , Taiyo Kikkawa 1 , Theo Dammaretz 1 , Ibuki Kawamata 2 , Yuki Suzuki 2, 3 , Shin-ichiro M. Nomura 2 , Satoshi Murata 2
Affiliation  

A new kind of the Vernier mechanism that is able to control the size of linear assembly of DNA origami nanostructures is proposed. The mechanism is realized by mechanical design of DNA origami, which consists of a hollow cylinder and a rotatable shaft in it connected through the same scaffold. This nanostructure stacks with each other by the shape complementarity at its top and bottom surfaces of the cylinder, while the number of stacking is limited by twisting angle of the shaft. Experiments have shown that the size distribution of multimeric assembly of the origami depends on the twisting angle of the shaft; the average lengths of the multimer are decamer, hexamer, and tetramer for 0°, 10°, and 20° twist, respectively. In summary, it is possible to affect the number of polymerization by adjusting the precise shape and movability of a molecular structure.

中文翻译:

旋转游标机构控制线性同聚物的大小

提出了一种新型的游标机制,该机制能够控制DNA折纸纳米结构的线性组装的大小。该机制是通过DNA折纸的机械设计实现的,该折纸包括一个空心圆柱和一个通过同一支架连接的可旋转轴。该纳米结构通过在圆柱体的顶表面和底表面处的形状互补而彼此堆叠,而堆叠的数量受到轴的扭转角的限制。实验表明,折纸的多头组件的尺寸分布取决于轴的扭转角度。对于扭曲0°,10°和20°,多聚体的平均长度分别为decamer,六聚体和四聚体。总之,
更新日期:2017-09-12
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