Allene moieties with axial chirality are featured in many natural products with biological activities. They also serve as unique building blocks in organic synthesis and as chiral ligands/catalysts. In recent years, chemists have made great efforts in the synthesis of chiral allenes, in particular with asymmetric catalytic methods. Significant progress has been achieved, although it still remains a challenging task. In this minireview article, we summarize the recent advances in the catalytic asymmetric synthesis of allenes.

中文翻译：

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丙二烯催化不对称合成的最新进展

在许多具有生物活性的天然产物中，具有轴向手性的异戊二烯部分具有特征。它们还用作有机合成中的独特结构单元和手性配体/催化剂。近年来，化学家在合成手性烯丙基方面做出了巨大的努力，特别是通过不对称催化方法。尽管仍然是一项艰巨的任务，但已经取得了重大进展。在这篇小型综述文章中，我们总结了丙二烯催化不对称合成的最新进展。