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Tracking Our Physical Inactivity and Progression to Death: Is This Evolutionary Stagnation?
Annals of Internal Medicine ( IF 39.2 ) Pub Date : 2017-09-12 , DOI: 10.7326/m17-2181
David A. Alter 1
Affiliation  

Progression is rarely linear. Once highly mobile hunters and gatherers, we have evolved into a technologically advanced but kinetically stagnant species. Sedentary societies define today's cultural norms (1). The adverse health outcomes associated with sedentary behavior have led many to conclude that sedentary behavior is a novel risk factor whose population-attributable risk may even surpass that of smoking (2). Others have interpreted such associations more cautiously, given inconsistencies in evidence across studies, measurement biases, residual confounding, ambiguity in explanatory intercausal pathway mechanisms, and the absence of clinical trials that are adequately powered to detect differences in mortality from sedentary interventions (3).


中文翻译:

跟踪我们的身体不活动和死亡进展:这是进化停滞吗?

级数很少是线性的。曾经是高度机动的猎人和采集者,我们已经发展成为技术先进但在动力学上停滞不前的物种。久坐的社会定义了当今的文化规范(1)。与久坐行为相关的不良健康后果已使许多人得出结论,久坐行为是一种新的危险因素,其归因于人群的危险甚至可能超过吸烟的危险(2)。鉴于研究中证据的不一致,测量偏差,残留混淆,解释性因果间通路机制的歧义以及缺乏足够的能力来检测久坐性干预导致的死亡率差异的临床试验,其他研究者更加谨慎地解释了这种关联(3)。
更新日期:2017-09-12
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