当前位置: X-MOL 学术J. Org. Chem. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Visible-Light Mediated Oxidative C–H/N–H Cross-Coupling between Tetrahydrofuran and Azoles Using Air
The Journal of Organic Chemistry ( IF 3.6 ) Pub Date : 2017-09-11 00:00:00 , DOI: 10.1021/acs.joc.7b01841
Lingling Zhang 1 , Hong Yi 1 , Jue Wang 1 , Aiwen Lei 1, 2
Affiliation  

Tetrahydrofuran is a privileged structural moiety in many important organic compounds. In this work, we have developed a simple and mild catalytic oxidative amination of tetrahydrofuran mediated by visible-light catalysis. The C(sp3)-H bond of tetrahydrofuran was activated using molecular oxygen as a benign oxidant. Besides, a variety of azoles could be tolerated, providing a green route for N-substituted azoles.

中文翻译:

四氢呋喃和唑在空气中的可见光介导的氧化性C–H / N–H交叉偶联

四氢呋喃是许多重要有机化合物中的特权结构部分。在这项工作中,我们开发了由可见光催化介导的四氢呋喃的简单温和催化氧化胺化反应。使用分子氧作为良性氧化剂激活四氢呋喃的C(sp3)-H键。此外,可以耐受多种吡咯,为N-取代的吡咯提供了绿色的途径。
更新日期:2017-09-11
down
wechat
bug