This study was performed to investigate the changes over time in polypropylene (PP) mesh explants from women with stress urinary incontinence originally treated with a midurethral PP sling. Following Institutional Review Board (IRB) approval, 10 PP explants removed for pain or obstructive symptoms between January and June 2016 were analyzed through various techniques to determine the degradation of the material in vivo. Exclusion criteria were exposed or infected mesh sling or sling in place for less than six months. One pristine control was studied for comparison. The explant samples were analyzed with scanning electron microscopy to visualize the surface defects as well as infrared spectroscopy and energy dispersive X-ray spectroscopy to determine if the degradation was oxidative in nature. The results show qualitative and quantitative bioerosion over the surface of the explant samples and an increase in the content of oxygen pointing toward oxidative degradation occurring in vivo.

中文翻译：

---

合成吊索外植体的生物侵蚀

进行这项研究的目的是调查最初使用中尿道PP悬吊带治疗的患有压力性尿失禁的女性的聚丙烯（PP）网状外植体随时间的变化。在机构审查委员会（IRB）批准后，通过各种技术分析了2016年1月至6月之间从疼痛或阻塞性症状中移除的10种PP外植体，以确定其在体内的降解。排除标准是暴露的或感染的网状吊索或就位吊索不到六个月。为了比较，研究了一种原始对照。用扫描电子显微镜对外植体样品进行分析以可视化表面缺陷，并通过红外光谱和能量色散X射线光谱分析来确定降解是否具有氧化性。