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The effects of house dust mite sublingual immunotherapy (SLIT)-tablet effects on immunological biomarkers and nasal allergen challenge symptoms
Journal of Allergy and Clinical Immunology ( IF 14.2 ) Pub Date : 2017-09-11 , DOI: 10.1016/j.jaci.2017.08.016 Natasha C Gunawardana 1 , Qing Zhao 2 , Leonidas N Carayannopoulos 2 , Kuenhi Tsai 2 , Vladislav A Malkov 2 , Diana Selverian 2 , Graham Clarke 3 , Tim Mant 3 , Brent D Butts 2 , Kaare Lund 4 , Trevor T Hansel 1 , Hendrik Nolte 2
Journal of Allergy and Clinical Immunology ( IF 14.2 ) Pub Date : 2017-09-11 , DOI: 10.1016/j.jaci.2017.08.016 Natasha C Gunawardana 1 , Qing Zhao 2 , Leonidas N Carayannopoulos 2 , Kuenhi Tsai 2 , Vladislav A Malkov 2 , Diana Selverian 2 , Graham Clarke 3 , Tim Mant 3 , Brent D Butts 2 , Kaare Lund 4 , Trevor T Hansel 1 , Hendrik Nolte 2
Affiliation
SQ HDM SLIT-tablet significantly increased serum HDM-specific IgG4 and IgE blocking factor, and significantly decreased early phase nasal symptoms after nasal allergen challenge. No significant effects on cytokines or gene expression in nasal mucosa were observed.
中文翻译：
屋尘螨舌下免疫疗法 (SLIT) 片剂对免疫生物标志物和鼻过敏原挑战症状的影响
SQ HDM SLIT-tablet 显着增加血清 HDM 特异性 IgG 4和 IgE 阻断因子，并显着降低鼻过敏原攻击后的早期鼻部症状。未观察到对鼻粘膜细胞因子或基因表达的显着影响。
更新日期：2017-09-11
中文翻译：
屋尘螨舌下免疫疗法 (SLIT) 片剂对免疫生物标志物和鼻过敏原挑战症状的影响
SQ HDM SLIT-tablet 显着增加血清 HDM 特异性 IgG 4和 IgE 阻断因子，并显着降低鼻过敏原攻击后的早期鼻部症状。未观察到对鼻粘膜细胞因子或基因表达的显着影响。
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