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Macitentan for the treatment of inoperable chronic thromboembolic pulmonary hypertension (MERIT-1): results from the multicentre, phase 2, randomised, double-blind, placebo-controlled study.
The Lancet ( IF 168.9 ) Pub Date : 2017-10-01 , DOI: 10.1016/s2213-2600(17)30305-3 Hossein-Ardeschir Ghofrani , Gérald Simonneau , Andrea M D'Armini , Peter Fedullo , Luke S Howard , Xavier Jaïs , David P Jenkins , Zhi-Cheng Jing , Michael M Madani , Nicolas Martin , Eckhard Mayer , Kelly Papadakis , Dominik Richard , Nick H Kim , Irene Lang , Christian Kähler , Marion Delcroix , Zoheir Bshouty , Pablo Sepulveda Varela , Zhi-Cheng Jing , Yuanhua Yang , Jinming Liu , Gangcheng Zhang , Nuofu Zhang , Yuhong Mi , Xianyang Zhu , Pavel Jansa , Xavier Jaïs , Grégoire Prévot , Hélène Bouvaist , Olivier Sanchez , Friedrich Grimminger , Matthias Held , Heinrike Wilkens , Stephan Rosenkranz , Ekkehard Grünig , Kristóf Karlócai , András Temesvári , Istvan Edes , Sigita Aidietienė , Skaidrius Miliauskas , Tomas Rene Pulido Zamudio , Carlos Jerjes Sanchez , Anton Vonk Noordegraaf , Jerzy Lewczuk , Piotr Podolec , Jarosław Kasprzak , Tatiana Mularek-Kubzdela , Ryszard Grzywna , Keertan Dheda , Olga Moiseeva , Alexander Chernyavskiy , Vladimir Shipulin , Olga Barbarash , Tamila Martynyuk , Hyung-Kwan Kim , Jun-Bean Park , Jae Seung Lee , Rudolf Speich , Silvia Ulrich , John-David Aubert , Arintaya Phrommintikul , Nattapong Jaimchariyatam , Suree Sompradeekul , Zeynep Pinar Onen , Gulfer Okumus , Lyubomyr Solovey , Volodymyr Gavrysyuk , Luke Howard , Joanna Pepke-Zaba , Robin Condliffe , John McConnell , Kim Kerr , Lan Hieu Nguyen , Nguyen Vinh Pham
The Lancet ( IF 168.9 ) Pub Date : 2017-10-01 , DOI: 10.1016/s2213-2600(17)30305-3 Hossein-Ardeschir Ghofrani , Gérald Simonneau , Andrea M D'Armini , Peter Fedullo , Luke S Howard , Xavier Jaïs , David P Jenkins , Zhi-Cheng Jing , Michael M Madani , Nicolas Martin , Eckhard Mayer , Kelly Papadakis , Dominik Richard , Nick H Kim , Irene Lang , Christian Kähler , Marion Delcroix , Zoheir Bshouty , Pablo Sepulveda Varela , Zhi-Cheng Jing , Yuanhua Yang , Jinming Liu , Gangcheng Zhang , Nuofu Zhang , Yuhong Mi , Xianyang Zhu , Pavel Jansa , Xavier Jaïs , Grégoire Prévot , Hélène Bouvaist , Olivier Sanchez , Friedrich Grimminger , Matthias Held , Heinrike Wilkens , Stephan Rosenkranz , Ekkehard Grünig , Kristóf Karlócai , András Temesvári , Istvan Edes , Sigita Aidietienė , Skaidrius Miliauskas , Tomas Rene Pulido Zamudio , Carlos Jerjes Sanchez , Anton Vonk Noordegraaf , Jerzy Lewczuk , Piotr Podolec , Jarosław Kasprzak , Tatiana Mularek-Kubzdela , Ryszard Grzywna , Keertan Dheda , Olga Moiseeva , Alexander Chernyavskiy , Vladimir Shipulin , Olga Barbarash , Tamila Martynyuk , Hyung-Kwan Kim , Jun-Bean Park , Jae Seung Lee , Rudolf Speich , Silvia Ulrich , John-David Aubert , Arintaya Phrommintikul , Nattapong Jaimchariyatam , Suree Sompradeekul , Zeynep Pinar Onen , Gulfer Okumus , Lyubomyr Solovey , Volodymyr Gavrysyuk , Luke Howard , Joanna Pepke-Zaba , Robin Condliffe , John McConnell , Kim Kerr , Lan Hieu Nguyen , Nguyen Vinh Pham
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Macitentan is beneficial for long-term treatment of pulmonary arterial hypertension. The microvasculopathy of chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary arterial hypertension are similar.
中文翻译：
Macitentan用于治疗无法手术的慢性血栓栓塞性肺动脉高压（MERIT-1）：多中心，2期，随机，双盲，安慰剂对照研究的结果。
Macitentan对长期治疗肺动脉高压有益。慢性血栓栓塞性肺动脉高压（CTEPH）和肺动脉高压的微血管病变相似。
更新日期：2017-09-11
中文翻译：
Macitentan用于治疗无法手术的慢性血栓栓塞性肺动脉高压（MERIT-1）：多中心，2期，随机，双盲，安慰剂对照研究的结果。
Macitentan对长期治疗肺动脉高压有益。慢性血栓栓塞性肺动脉高压（CTEPH）和肺动脉高压的微血管病变相似。
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