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Effects of Coffee Consumption on Fasting Blood Glucose and Insulin Concentrations
Diabetes Care ( IF 16.2 ) Pub Date : 2004-12-01 , DOI: 10.2337/diacare.27.12.2990
Rob M. van Dam 1 , Wilrike J. Pasman 2 , Petra Verhoef 3, 4
Affiliation  

Higher habitual coffee consumption was associated with higher insulin sensitivity (1) and a lower risk for type 2 diabetes (2–6) in diverse populations. In contrast, short-term metabolic studies showed that caffeine intake can acutely lower insulin sensitivity (7–9) and increase glucose concentrations (10–15). Randomized intervention studies are needed to examine whether tolerance to these acute effects develops after longer-term consumption (16). We therefore examined the effects of coffee and caffeine on fasting blood concentrations of glucose and insulin over 2–4 weeks in two crossover studies in healthy volunteers.

中文翻译:

咖啡摄入量对空腹血糖和胰岛素浓度的影响

在不同人群中,习惯性咖啡消费量的增加与较高的胰岛素敏感性(1)和2型糖尿病的风险较低(2–6)相关。相反,短期代谢研究表明,摄入咖啡因会严重降低胰岛素敏感性(7-9)并增加葡萄糖浓度(10-15)。需要进行随机干预研究,以检查长期服用后是否对这些急性效应产生了耐受性(16)。因此,我们在两项健康志愿者的交叉研究中检查了咖啡和咖啡因对2至4周内空腹血糖和胰岛素浓度的影响。
更新日期:2017-09-08
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