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Putting Two Heads Together to Build a Better Brain.
Cell Stem Cell ( IF 23.9 ) Pub Date : 2017-Sep-07 , DOI: 10.1016/j.stem.2017.08.017
John K. Mich , Jennie L. Close , Boaz P. Levi

3D organoids enable in vitro human brain development models, but they have not yet recapitulated some essential features of brain circuit formation. Recently, several studies appearing in Nature, Nature Methods, and Cell Stem Cell generated fused organoid models of inhibitory and excitatory neuron development, which can now achieve functional circuit integration.

中文翻译:

把两个脑袋放在一起,建立一个更好的大脑。

3D类器官可实现体外人脑发育模型,但它们尚未概括出脑回路形成的一些基本特征。最近,在《自然》,《自然方法》和《细胞干》中出现了几项研究。细胞生成了抑制性和兴奋性神经元发育的融合类器官模型,现在可以实现功能电路的整合。
更新日期:2017-09-07
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