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Synthetic lethality screens point the way to new cancer drug targets
Nature Reviews Drug Discovery ( IF 120.1 ) Pub Date :  , DOI: 10.1038/nrd.2017.165
Asher Mullard

Synthetic lethality screens point the way to new cancer drug targets

Nature Reviews Drug Discovery, Published online: 1 September 2017; doi:10.1038/nrd.2017.165

A resurgence in synthetic lethality screening, enabled by CRISPR gene editing, is unlocking targeted drugs for patients with cancerous loss-of-function mutations.



中文翻译:

合成杀伤力筛查为新的癌症药物靶标指明了道路

合成杀伤力筛查为新的癌症药物靶标指明了道路

Nature Reviews Drug Discovery,在线发布:2017年9月1日;doi:10.1038 / nrd.2017.165

通过CRISPR基因编辑实现的合成致死性筛查的兴起,正在为具有癌症功能丧失突变的患者提供靶向药物。

更新日期:2017-09-07
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