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Suzuki–Miyaura Cross-Coupling Reactions of Tetrahydroxanthones and 4-Chromanone Lactones to Heteromeric Biaryls
Advanced Synthesis & Catalysis ( IF 5.4 ) Pub Date : 2017-09-07 06:00:43 , DOI: 10.1002/adsc.201700497
Larissa Geiger 1 , Martin Nieger 2 , Stefan Bräse 1, 3
Affiliation  

We are reporting on a Suzuki–Miyaura cross-coupling study of a tetrahydroxanthone model system with different boronic acids, pinacolboranes, and halides to afford heteromeric biaryls. We transferred these reaction conditions to the Suzuki–Miyaura cross-coupling reactions of 4-chromanone lactones. We thereby obtained complex building blocks offering a convenient starting point for further transformations towards various natural products with the tetrahydroxanthone structural motif.

中文翻译:

Suzuki-Miyaura四氢黄嘌呤和4-色曼酮内酯与异聚联芳烃的交叉偶联反应

我们正在报告Suzuki-Miyaura对四氢蒽酮模型系统与不同的硼酸,频哪醇和卤化物的交联研究,以提供杂聚联芳基。我们将这些反应条件转移到4-chromanone内酯的Suzuki-Miyaura交叉偶联反应中。因此,我们获得了复杂的构建基块,为进一步转化为具有四氢蒽酮结构图案的各种天然产物提供了便利的起点。
更新日期:2017-09-07
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