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Micelles: Multifunctional Polymeric Micelles for Combining Chelation and Detection of Iron in Living Cells (Adv. Healthcare Mater. 17/2017)
Advanced Healthcare Materials ( IF 10.0 ) Pub Date : 2017-09-06 , DOI: 10.1002/adhm.201770087
Zhi Liu 1 , Max Purro 1, 2 , Jing Qiao 1 , May P. Xiong 1
Affiliation  

May P. Xiong and co‐workers construct multifunctional Pluronics F127 micelles for iron chelation and fluorescence detection by introducing tetraphenylethene and the chelating drug deferoxamine into self‐assembling polymeric micelles in article 1700162. Deferoxamine can simultaneously be used to chelate iron(III) and quench the fluorescence emission of tetraphenylethene. This fluorescence “turn‐off” process can be used to monitor the iron chelation process in an iron overload cell model.
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中文翻译:

胶束:用于结合螯合和检测活细胞中铁的多功能聚合胶束(Adv。Healthcare Mater。17/2017)

May P. Xiong和他的同事们通过在文章1700162中将四苯乙烯和螯合剂去铁胺引入自组装聚合物胶束中来构建多功能的Pluronics F127胶束,用于铁螯合和荧光检测。去铁胺可同时用于螯合铁(III)和淬灭四苯基乙烯的荧光发射。这种荧光“关闭”过程可用于监控铁超负荷电池模型中的铁螯合过程。
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更新日期:2017-09-06
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