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Live-Cell Nanoscopy in Antiadhesion Therapy
Trends in Microbiology ( IF 15.9 ) Pub Date : 2017-05-08 , DOI: 10.1016/j.tim.2017.04.002
Joan A. Geoghegan , Timothy J. Foster , Pietro Speziale , Yves F. Dufrêne

Live-cell nanoscopy has contributed significantly to assessing the inhibition of adhesion of uropathogenic Escherichia coli and Staphylococcus aureus by glycoconjugates and monoclonal antibodies, respectively, and of S. aureus surface attachment and cell–cell association by a synthetic peptide. This new technology shows promise for the development of antiadhesion therapies against bacterial pathogens.



中文翻译:

活细胞纳米技术在抗粘连治疗中的作用

活细胞纳米显微镜显着地评估了糖结合物和单克隆抗体对尿毒症性大肠杆菌金黄色葡萄球菌粘附的抑制作用,以及合成肽对金黄色葡萄球菌表面附着和细胞间结合的抑制作用。这项新技术显示出有望开发针对细菌病原体的抗粘连疗法。

更新日期:2017-05-08
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