Organic nanoparticle-based (ONP) gene therapy is a potential strategy to cure human cancer. However, there are still many practical barriers before the promising results from in vitro and preclinical studies can be translated to clinical success. We discuss the reasons behind the hesitant uptake by the clinic.

中文翻译：

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基于纳米粒子的基因治疗在临床翻译中的局限性

基于有机纳米粒子（ONP）的基因疗法是治疗人类癌症的潜在策略。但是，在将体外和临床前研究的有希望的结果转化为临床成功之前，仍然存在许多实际障碍。我们讨论了诊所犹豫不决的原因。