Chronic obstructive pulmonary disease (COPD) is a progressive lung disease characterized by pathophysiological factors including airflow limitation, hyperinflation and reduced gas exchange. Treatment consists of lifestyle changes, lung rehabilitation and pharmacological therapies such as long acting beta-2-agonists (LABA) and long acting muscarinic antagonists (LAMA). More recently bronchoscopic treatments are emerging for COPD. Among them endobronchial valves (EBV) and endobronchial coils (EBC), next to endobronchial stents, sclerosing agents, targeted lung denervation and liquid nitrogen metered cryospray. In this review we aim to summarize the new emerging bronchoscopic treatments and their effect sizes compared with lung rehabilitation and pharmacological therapies.

慢性阻塞性肺疾病（COPD）是一种进行性肺部疾病，其特征在于病理生理因素，包括气流受限，过度充气和气体交换减少。治疗包括改变生活方式，肺部康复和药理疗法，例如长效β-2-激动剂（LABA）和长效毒蕈碱拮抗剂（LAMA）。最近，针对COPD的支气管镜治疗正在兴起。其中，支气管内瓣膜（EBV）和支气管内线圈（EBC），紧接支气管内支架，硬化剂，靶向肺去神经支配和液氮定量冷冻喷雾。在这篇综述中，我们旨在总结与肺康复和药物治疗相比新兴的支气管镜治疗方法及其效果大小。