Proteins often act in complexes assembled via protein–protein interaction domains. The sterile alpha motif (SAM) domain is one of the most prominent interaction domains in animals and is present in proteins of diverse functions. This domain allows head-to-tail closed oligomerisation or polymer formation resulting in homo- and/or heterocomplexes that have been shown to be important for proper protein localisation and function. In plants this domain is also present but has been poorly studied except for recent studies on the LEAFY floral regulator and the tRNA import component (TRIC)1/2 proteins. Here we catalogue SAM domain-containing proteins from arabidopsis (Arabidopsis thaliana), compare plant and other eukaryotic SAM domains, and perform homology modelling to probe plant SAM domain interaction capabilities.

蛋白质通常在通过蛋白质-蛋白质相互作用域组装的复合物中起作用。无菌α基序（SAM）域是动物中最突出的相互作用域之一，存在于多种功能的蛋白质中。该结构域允许从头到尾的封闭低聚或形成聚合物，从而导致均聚物和/或杂合物被证明对适当的蛋白质定位和功能很重要。在植物中也存在该结构域，但除最近对LEAFY花卉调节剂和tRNA导入成分（TRIC）1/2蛋白的研究外，研究很少。在这里，我们对来自拟南芥（拟南芥）的含SAM结构域的蛋白质进行分类），比较植物和其他真核SAM域，并进行同源性建模以探查植物SAM域的相互作用能力。