The American Thoracic Society (ATS) and European Respiratory Society (ERS) should be congratulated on updating standards for diffusing capacity of the lung for carbon monoxide (DLCO) [1]. I agree that “Besides varying with age, sex, height and possible ethnicity, DLCO also changes with Hb, lung volume, COHb, PIO2 …, exercise and body position.” and that “adjustments for these factors be made in the predicted rather than the measured DLCO”. Reporting transfer coefficient of the lung for carbon monoxide (KCO) rather than DLCO/alveolar volume (VA) will help get away from the mistaken notion that DLCO/VA “corrects” DLCO for lung volume [2]. While the new standards describe how to adjust predicted DLCO for haemoglobin (Hb), COHb and inspired oxygen tension (PIO2), it does not discuss how to adjust predicted DLCO and KCO for lung volume. DLCO reports and interpretation should be standardised and include adjusting predicted DLCO and KCO for lung volume http://ow.ly/ywTA30cOh44

中文翻译：

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D LCO：调整肺容量、标准化报告和解释

美国胸科学会 (ATS) 和欧洲呼吸学会 (ERS) 更新了肺一氧化碳扩散能力 (DLCO) 的标准 [1]。我同意“除了随年龄、性别、身高和可能的种族而变化外，DLCO 还随 Hb、肺容量、COHb、PIO2 ……、运动和身体姿势而变化。” 并且“在预测的而不是测量的 DLCO 中对这些因素进行调整”。报告一氧化碳 (KCO) 的肺转移系数而不是 DLCO/肺泡容积 (VA) 将有助于摆脱 DLCO/VA “校正”肺容积的 DLCO 的错误观念 [2]。虽然新标准描述了如何调整血红蛋白 (Hb)、COHb 和吸入氧张力 (PIO2) 的预测 DLCO，但并未讨论如何调整肺容量的预测 DLCO 和 KCO。