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High-Dose Vitamin D3 during Tuberculosis Treatment in Mongolia. A Randomized Controlled Trial
American Journal of Respiratory and Critical Care Medicine ( IF 24.7 ) Pub Date : 2017-09-01 , DOI: 10.1164/rccm.201705-0936ocpubmed:28692301
Davaasambuu Ganmaa, Baatar Munkhzul, Wafaie Fawzi, Donna Spiegelman, Walter C. Willett, Purev Bayasgalan, Erkhembayar Baasansuren, Burneebaatar Buyankhishig, Sereeter Oyun-Erdene, David A. Jolliffe, Theodoros Xenakis, Sabri Bromage, Barry R. Bloom, Adrian R. Martineau

Rationale: Existing trials of adjunctive vitamin D in the treatment of pulmonary tuberculosis (PTB) are variously limited by small sample sizes, inadequate dosing regimens, and high baseline vitamin D status among participants. Comprehensive analyses of the effects of genetic variation in the vitamin D pathway on response to vitamin D supplementation are lacking.

中文翻译:

蒙古在结核病治疗期间的大剂量维生素D 3。随机对照试验

理由:现有的辅助性维生素D治疗肺结核(PTB)的试验受到样本量小,给药方案不足以及参与者中较高的基线维生素D状态的限制。缺乏对维生素D途径的遗传变异对补充维生素D的反应的影响的综合分析。
更新日期:2017-09-05
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