Rationale: The rate of decline of lung function is greater than age-related change in a substantial proportion of patients with chronic obstructive pulmonary disease, even after smoking cessation. Regions of the lung adjacent to emphysematous areas are subject to abnormal stretch during respiration, and this biomechanical stress likely influences emphysema initiation and progression.

中文翻译：

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慢性阻塞性肺疾病的肺部X线计算机断层扫描测量及肺功能下降

理由：即使在戒烟后，在相当一部分慢性阻塞性肺疾病患者中，肺功能下降的速度也要大于与年龄相关的变化。邻近肺气肿区域的肺区域在呼吸过程中会出现异常拉伸，这种生物力学应力可能会影响肺气肿的发生和发展。