This work demonstrates the extraction potential of carboxylated carbon nanospheres (CNSs-COOH) for solid-phase extraction of perfluoroalkyl acids (PFAAs) for the first time. Six PFAAs, including perfluorohexanesulfonate (PFHxS), perfluoroheptanoic acid (PFHpA), perfluorooctanoic acid (PFOA), perfluorooctanoic sulfonic (PFOS), perfluorononanoic acid (PFNA) and perfluorodecanoic acid (PFDA), were quantitatively adsorbed on a CNSs-COOH-packed cartridge; then, the PFAAs retained on the adsorbent were quantitatively eluted with an optimized volume of acetone (pH = 10). Finally, the desorbed PFAAs were determined by liquid chromatography–tandem mass spectrometry. Important relevant factors, such as the eluant and its volume, sample pH, amount of CNSs-COOH, sample flow rate and sample volume were optimized in detail. Under the optimized conditions, low limits of detection (0.01–1.2 ng L⁻¹), wide linear range (0.50–200 ng L⁻¹) and good repeatability (2.4–5.1%) and good reproducibility (3.7–8.8%) were obtained. The proposed method was applied to analyze the six PFAAs in real environmental water samples, and satisfactory results were achieved. All of these results showed that CNSs-COOH will be a good choice for the pre-concentration and analysis of target PFAAs at trace levels in environmental water samples in the future.

这项工作首次证明了羧化碳纳米球（CNSs-COOH）的固相萃取全氟烷基酸（PFAAs）的萃取潜力。装有全氟己烷磺酸（PFHxS），全氟庚酸（PFHpA），全氟辛酸（PFOA），全氟辛磺酸（PFOS），全氟壬酸（PFNA）和全氟癸酸（PFDA）的6种PFAA被定量吸附在装满CNSs-COOH的小柱上; 然后，用最适量的丙酮（pH = 10）定量洗脱保留在吸附剂上的PFAA。最后，通过液相色谱-串联质谱法测定了解吸的PFAA。详细优化了重要的相关因素，例如洗脱液及其体积，样品pH，CNSs-COOH的量，样品流速和样品量。在优化的条件下，^-1），宽线性范围（0.50-200 ng L ^-1），良好的重复性（2.4-5.1％）和良好的重现性（3.7-8.8％）。将该方法用于实际环境水样中的六种PFAA分析，取得了满意的结果。所有这些结果表明，CNSs-COOH将是将来对环境水样品中痕量水平的目标PFAA进行预浓缩和分析的理想选择。