SEE PAGE 1339 S tudents who completed high school physics class remember Ohm’s Law: V 1⁄4 I R, where V 1⁄4 voltage, I 1⁄4 current, and R 1⁄4 resistance. Transposed to the cardiovascular system, this law is stated as BP 1⁄4 CO TPR, where BP 1⁄4 blood pressure, CO 1⁄4 cardiac output, and TPR 1⁄4 total peripheral resistance. Chatterjee et al. (1) and others recognized that the reduced CO that occurred following myocardial infarction led to a reflexive increase in TPR, further impeding CO. In decompensated myocardial infarction patients, administration of vasodilators significantly reduced TPR, simultaneously increasing stroke volume, leading to hemodynamic improvement. In the years that followed, the principle of afterload reduction has been applied successfully in multiple clinical settings of reduced CO.

中文翻译：

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评估主动脉瓣狭窄患者的抵抗力

参见第 1339 页 完成了高中物理课的学生记住了欧姆定律：V 1⁄4 IR，其中 V 1⁄4 电压、I 1⁄4 电流和 R 1⁄4 电阻。转换到心血管系统，该定律被表述为 BP 1⁄4 CO TPR，其中 BP 1⁄4 血压、CO 1⁄4 心输出量和 TPR 1⁄4 总外周阻力。查特吉等人。(1) 等人认识到，心肌梗塞后发生的 CO 减少导致 TPR 反射性增加，进一步阻碍 CO。在失代偿心肌梗塞患者中，血管扩张剂的给药显着降低 TPR，同时增加每搏输出量，导致血流动力学改善。在随后的几年中，减少后负荷的原则已成功应用于减少 CO 的多个临床环境中。