mary outcomes of all 7 T-Trials were powered at 90%, so both positive and negative results are both meaningful and reliable. The T-Trials therefore provided considerable new information about the efficacy of testosterone in symptomatic older men with low testosterone. The T-Trials population was not large enough nor the duration of observation long enough to provide definitive information about the risks of this treatment. We therefore agree with Dr Haring that a larger, longer, placebo-controlled trial is needed to determine the risks of testosterone treatment in older men with low testosterone.

中文翻译：

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睾酮替代疗法和心血管风险——对其他参数的仔细观察

所有 7 项 T 试验的主要结果的功效为 90%，因此阳性和阴性结果均有意义且可靠。因此，T 试验提供了大量关于睾酮对睾酮低的有症状老年男性的疗效的新信息。T-Trials 人群不够大，观察时间也不够长，无法提供有关这种治疗风险的明确信息。因此，我们同意 Haring 博士的观点，即需要进行更大规模、更长时间、安慰剂对照的试验来确定睾酮水平低的老年男性接受睾酮治疗的风险。