Injurious Falls and Syncope in Older Community-Dwelling Adults Meeting Inclusion Criteria for SPRINT The Systolic Blood Pressure Intervention Trial (SPRINT) demonstrated that treating adults 75 years of age or older with hypertension to reach a systolic blood pressure target of less than 120 mm Hg compared with a systolic blood pressure target of less than 140 mm Hg reduced the numbers of cardiovascular events and death without a significant increase in the number of injurious falls or syncope.1 However, prior to the adoption of an intensive strategy to lower systolic blood pressure in the oldest segment of the population, it is prudent to determine if individuals meeting inclusion criteria for SPRINT outside the clinical trial context are similar to trial participants, especially with regard to risk for adverse outcomes. We used The Irish Longitudinal Study on Ageing2,3 (TILDA) to compare baseline rates of injurious falls and syncope in community-dwelling older adults with the rates in the standard care group of SPRINT.

中文翻译：

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符合 SPRINT 纳入标准的老年社区居民的伤害性跌倒和晕厥

符合 SPRINT 纳入标准的老年社区居民的伤害性跌倒和晕厥 收缩压干预试验 (SPRINT) 表明，治疗 75 岁或以上患有高血压的成年人可达到低于 120 mmHg 的收缩压目标收缩压目标低于 140 mmHg 可减少心血管事件和死亡的数量，而不会显着增加跌倒或晕厥的数量。1 然而，在采用强化策略降低收缩压之前，作为人口中年龄最大的部分，谨慎地确定在临床试验环境之外符合 SPRINT 纳入标准的个体是否与试验参与者相似，尤其是在不良结果风险方面。我们使用爱尔兰老龄化纵向研究 2,3 (TILDA) 来比较社区老年人的伤害性跌倒和晕厥的基线发生率与 SPRINT 标准护理组的发生率。