The excess of halide ions (F⁻, Cl⁻, Br⁻, I⁻) can cause adverse effects. Earlier studies demonstrated time-dependent stimulations of organic salts with halide ions on photobacteria. Therefore, inorganic ones with halide ions (e.g., NaX, X = F⁻, Cl⁻, Br⁻, I⁻) were assumed to cause similar effects. In the present study, Vibrio fischeri was exposed to NaX. Results showed that the contents of favin mono-nucleotide (FMN), nicotinamide adenine dinucleotide (NADH), and nicotinamide adenine dinucleotide phosphate (NADPH) were stimulated by NaX with a time-dependent fashion. The maximum stimulations on FMN at 24 h were 172%, 168%, 211% and 298% of the control (p < 0.05) in NaF, NaCl, NaBr and NaI, respectively, with an order of NaF ≈ NaCl < NaBr < NaI. The maximum stimulations on NAD(P)H at 24 h followed similar orders. Similar time-dependent stimulatory effects were observed in the FMN:NAD(P)H reaction catalyst (luciferase, in the form of expression levels of lux A and lux B), adenosine triphosphate and the expression levels of its regulating gene adk. The luminescent stimulations were significantly higher than the biochemical ones despite of similar time-dependence and stimulation order among NaX. The overall results showed a common hormetic pattern in sodium halide salts.

中文翻译：

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费氏弧菌中卤化钠盐对氧化还原反应物，能量供应和发光的时间依赖性刺激

卤离子的过量（F ^- ，氯^- ，溴^- ，我^- ）可能会导致不利的影响。较早的研究表明卤化物离子对光细菌的有机盐刺激具有时间依赖性。因此，（与卤化物离子无机那些例如，的NaX，X = F ^- ，氯^- ，溴^- ，我^- ）被假定为引起相似的效果。在本研究中，费氏弧菌暴露于NaX。结果表明，NaX刺激了Favin单核苷酸（FMN），烟酰胺腺嘌呤二核苷酸（NADH）和烟酰胺腺嘌呤二核苷酸磷酸（NADPH）的含量，并具有时间依赖性。在NaF，NaCl，NaBr和NaI中，FMN在24 h时的最大刺激分别为对照的172％，168％，211％和298％（p <0.05），其顺序为NaF≈NaCl <NaBr <NaI 。在24小时对NAD（P）H的最大刺激遵循相似的顺序。在FMN：NAD（P）H反应催化剂（萤光素酶，以lux A和lux B的表达水平形式），三磷酸腺苷及其调节基因adk的表达水平中观察到了类似的时间依赖性刺激作用。。尽管NaX之间的时间依赖性和刺激顺序相似，但发光刺激显着高于生化刺激。总体结果显示出卤化钠盐中常见的钟表模式。