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Synthesis and Anticancer Evaluation of 2,3-Disubstituted Indoles Derived from Azobenzenes and Internal Olefins
European Journal of Organic Chemistry ( IF 2.8 ) Pub Date : 2017-09-01 06:36:08 , DOI: 10.1002/ejoc.201701001 Yongguk Oh 1 , Sang Hoon Han 1 , Neeraj Kumar Mishra 1 , Umasankar De 1 , Junho Lee 1 , Hyung Sik Kim 1 , Young Hoon Jung 1 , In Su Kim 1
European Journal of Organic Chemistry ( IF 2.8 ) Pub Date : 2017-09-01 06:36:08 , DOI: 10.1002/ejoc.201701001 Yongguk Oh 1 , Sang Hoon Han 1 , Neeraj Kumar Mishra 1 , Umasankar De 1 , Junho Lee 1 , Hyung Sik Kim 1 , Young Hoon Jung 1 , In Su Kim 1
Affiliation
Azo-directed rhodium(III)-catalysed C–H functionalization and intramolecular annulation reactions between azobenzenes and internal olefins are described. The resulting indoles were evaluated for in-vitro anticancer activity against various human cancer cell lines.
中文翻译:
偶氮苯和内部烯烃衍生的2,3-二取代吲哚的合成及抗癌评价
偶氮苯和内烯烃之间的偶氮定向铑(III)催化的CH功能化和分子内的环化反应进行了描述。评价所得的吲哚对各种人类癌细胞系的体外抗癌活性。
更新日期:2017-09-04
中文翻译:
偶氮苯和内部烯烃衍生的2,3-二取代吲哚的合成及抗癌评价
偶氮苯和内烯烃之间的偶氮定向铑(III)催化的CH功能化和分子内的环化反应进行了描述。评价所得的吲哚对各种人类癌细胞系的体外抗癌活性。