The timing of drug administration in relation to meals could have a major effect on bioavailability and plasma concentrations of oral oncology drugs. The Comment by Floor J E Lubberman and colleagues¹ provides a timely discussion on the effect of different types of fasting regimens in oncology trials on drug exposure and anticancer treatment. However, some information and arguments should be clarified.

中文翻译：

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临床肿瘤学试验和药物标记中的禁食条件

与进餐有关的药物给药时间可能会对口服肿瘤药物的生物利用度和血浆浓度产生重大影响。Floor JE Lubberman及其同事¹的评论对肿瘤试验中不同类型的禁食方案对药物暴露和抗癌治疗的影响进行了及时的讨论。但是，应澄清一些信息和论点。