We report here an efficient, mild and green protocol for the chemoselective oxidization of benzylic CH bonds. The reactions were carried out with ZIF-67 as heterogeneous catalyst and tert-butyl hydroperoxide as an oxidant. The desired ketones were achieved in moderate to excellent yields at room temperature under solvent-free and open-flask conditions. Notably, the presented method avoids the use of complex catalyst, toxic organic solvent, additives and high temperature. At the same time, the heterogeneous catalyst could be conveniently reused at least six cycles without significantly decreasing yield of desired product. The gram-scale experiments were achieved with excellent yields and provided a modest and effective method for scale up applications.

我们在这里报告了苄基C H键的化学选择性氧化的一种有效，温和和绿色的协议。用ZIF-67作为非均相催化剂和叔丁基氢过氧化物作为氧化剂进行反应。在室温下在无溶剂和开瓶条件下以中等至极好的收率获得了所需的酮。值得注意的是，所提出的方法避免了使用复杂的催化剂，有毒的有机溶剂，添加剂和高温。同时，该多相催化剂可以方便地重复使用至少六个循环而不会显着降低所需产物的产率。克级实验以极好的收率实现，并为扩大规模的应用提供了适度而有效的方法。