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Introduction to the Theme “New Methods and Novel Therapeutic Approaches in Pharmacology and Toxicology”
Annual Review of Pharmacology and Toxicology ( IF 12.5 ) Pub Date : 2017-01-06 00:00:00 , DOI: 10.1146/annurev-pharmtox-091616-023708
Paul A. Insel 1, 2 , Susan G. Amara 3 , Terrence F. Blaschke 4 , Urs A. Meyer 5
Affiliation  

Major advances in scientific discovery and insights can result from the development and use of new techniques, as exemplified by the work of Solomon Snyder, who writes a prefatory article in this volume. The Editors have chosen “New Methods and Novel Therapeutic Approaches in Pharmacology and Toxicology” as the Theme for a number of articles in this volume. These include ones that review the development and use of new experimental tools and approaches (e.g., nanobodies and techniques to explore protein-protein interactions), new types of therapeutics (e.g., aptamers and antisense oligonucleotides), and systems pharmacology, which assembles (big) data derived from omics studies together with information regarding drugs and patients. The application of these new methods and therapeutic approaches has the potential to have a major impact on basic and clinical research in pharmacology and toxicology as well as on patient care.

中文翻译:


主题“药理毒理学的新方法和新治疗方法”简介

科学发现和见解的重大进步可以归功于新技术的开发和使用,所罗门·斯奈德(Solomon Snyder)的工作就证明了这一点,他在本卷中撰写了一篇引人注目的文章。编辑选择了“药理学和毒理学中的新方法和新治疗方法”作为本卷中许多文章的主题。其中包括审查新实验工具和方法(例如,探索蛋白质-蛋白质相互作用的纳米抗体和技术),新型治疗剂(例如,适体和反义寡核苷酸)和组合的系统药理学的开发和使用的方法。 )从组学研究中获得的数据以及有关药物和患者的信息。

更新日期:2017-01-06
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